您可以尝试创建一个函数来替换普通单词的重音符号。
架构（mysql v5.6）

CREATE TABLE main_creditperson(id int,name Nvarchar(50));

INSERT INTO main_creditperson VALUES (366354,N'Irene Olga López');

ALTER TABLE main_creditperson 
MODIFY name VARCHAR(50) CHARACTER SET utf8mb4      
      COLLATE utf8mb4_bin; 

DROP FUNCTION IF EXISTS fn_remove_accents;
DELIMITER |
CREATE FUNCTION fn_remove_accents( textvalue VARCHAR(10000) ) RETURNS VARCHAR(10000)

BEGIN

    SET @textvalue = textvalue;

    -- ACCENTS
    SET @withaccents = 'ŠšŽžÀÁÂÃÄÅÆÇÈÉÊËÌÍÎÏÑÒÓÔÕÖØÙÚÛÜÝŸÞàáâãäåæçèéêëìíîïñòóôõöøùúûüýÿþƒ';
    SET @withoutaccents = 'SsZzAAAAAAACEEEEIIIINOOOOOOUUUUYYBaaaaaaaceeeeiiiinoooooouuuuyybf';
    SET @count = LENGTH(@withaccents);

    WHILE @count > 0 DO
        SET @textvalue = REPLACE(@textvalue, SUBSTRING(@withaccents, @count, 1), SUBSTRING(@withoutaccents, @count, 1));
        SET @count = @count - 1;
    END WHILE;

    SET @special = '!@#$%¨&*()_+=§¹²³£¢¬"`´{[^~}]<,>.:;?/°ºª+*|\\''';
    SET @count = LENGTH(@special);

    WHILE @count > 0 do
        SET @textvalue = REPLACE(@textvalue, SUBSTRING(@special, @count, 1), '');
        SET @count = @count - 1;
    END WHILE;

    RETURN @textvalue;

END
|
DELIMITER ;

查询#1

SELECT id,fn_remove_accents(name)  name
FROM main_creditperson 
WHERE name="Irene Olga López";

| id     | name             |
| ------ | ---------------- |
| 366354 | Irene Olga Lopez |

db fiddle视图
函数引用

如果 COLLATION 有什么问题吗 ..._ci 变体，则在比较时忽略重音符号。也就是说，不需要重音消除代码。