我们可以先去掉开头/结尾的空格，然后用逗号替换空格：

import re

sentence = ['He must be having a great time\n                           ', 'It is fun to play chess      ', 'Sometimes TT is better than Badminton             ']
output = [re.sub(r'\s+', ',', x.strip()) for x in sentence]
print(output)

这将打印：

['He,must,be,having,a,great,time',
 'It,is,fun,to,play,chess',
 'Sometimes,TT,is,better,than,Badminton']

您可以使用更简单的split/join方法（时间：1.48微秒± 74纳秒）。
str.split()将按空格字符组（例如空格或换行符）进行拆分。
str.join(iter)将把iter的元素与它所使用的字符串连接起来。
演示：

sentence = [
    "He must be having a great time\n                           ",
    "It is fun to play chess      ",
    "Sometimes TT is better than Badminton             ",
]
[",".join(s.split()) for s in sentence]

给予

['He,must,be,having,a,great,time',
 'It,is,fun,to,play,chess',
 'Sometimes,TT,is,better,than,Badminton']

第二种方法，strip/replace（时间：1.56微秒± 107纳秒）。
str.strip()删除str开头和结尾的所有空白字符。
str.replace(old, new)将str中所有出现的old替换为new（之所以有效，是因为字符串中的单词之间只有一个空格）。
演示：

sentence = [
    "He must be having a great time\n                           ",
    "It is fun to play chess      ",
    "Sometimes TT is better than Badminton             ",
]

[s.strip().replace(" ", ",") for s in sentence]

给予

['He,must,be,having,a,great,time',
 'It,is,fun,to,play,chess',
 'Sometimes,TT,is,better,than,Badminton']

def eliminating_white_spaces(list):
for string in range(0,len(list)):
    if ' ' in list[string] and string+1==len(list):
        pass
    else:  
        list[string]=str(list[string]).replace(' ',',')
return list