我不太确定您的问题的用例是什么，但您可以通过手动调整时区偏移量来实现。
就像这样：

const timeStr = '2022-11-04T20:45:35+04:00'
const time = moment(timeStr)

// get the offset from the time string
const offset = timeStr.slice(-6)

// set the timezone offset (so that in case it doesn't match your local time, it's corrected)
time.utcOffset(offset)

// add the offset time, and convert to UTC
time.add(time.utcOffset(), 'minutes').utc()
console.log(time)

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