使用将扩展变量内容的格式字符串：

file.write(f'game {i}, {result}')

虽然我会使用csv模块，因为它可以正确处理带有分隔符和/或引号的数据列：

import csv
with open('data.csv', 'w', newline='') as file:
    writer = csv.writer(file)
    for i in range(10):
        result = 'some result with , and " in it'
        writer.writerow([f'game {i}', result])

正确使用逗号将结果引起来并转义嵌入引号的输出：

game 0,"some result with , and "" in it"
game 1,"some result with , and "" in it"
game 2,"some result with , and "" in it"
game 3,"some result with , and "" in it"
game 4,"some result with , and "" in it"
game 5,"some result with , and "" in it"
game 6,"some result with , and "" in it"
game 7,"some result with , and "" in it"
game 8,"some result with , and "" in it"
game 9,"some result with , and "" in it"

要读取和解析数据：

with open('data.csv', 'r', newline='') as file:
    reader = csv.reader(file)
    for game, result in reader:
        print(game, result)