试试这个代码

Microsoft.Office.Interop.Excel.Application oXL;
Microsoft.Office.Interop.Excel._Workbook oWB;
Microsoft.Office.Interop.Excel._Worksheet oSheet;
Microsoft.Office.Interop.Excel.Range oRng;
object misvalue = System.Reflection.Missing.Value;
try
{
    //Start Excel and get Application object.
    oXL = new Microsoft.Office.Interop.Excel.Application();
    oXL.Visible = true;

    //Get a new workbook.
    oWB = (Microsoft.Office.Interop.Excel._Workbook)(oXL.Workbooks.Add(""));
    oSheet = (Microsoft.Office.Interop.Excel._Worksheet)oWB.ActiveSheet;

    //Add table headers going cell by cell.
    oSheet.Cells[1, 1] = "First Name";
    oSheet.Cells[1, 2] = "Last Name";
    oSheet.Cells[1, 3] = "Full Name";
    oSheet.Cells[1, 4] = "Salary";

    //Format A1:D1 as bold, vertical alignment = center.
    oSheet.get_Range("A1", "D1").Font.Bold = true;
    oSheet.get_Range("A1", "D1").VerticalAlignment =
        Microsoft.Office.Interop.Excel.XlVAlign.xlVAlignCenter;

    // Create an array to multiple values at once.
    string[,] saNames = new string[5, 2];

    saNames[0, 0] = "John";
    saNames[0, 1] = "Smith";
    saNames[1, 0] = "Tom";

    saNames[4, 1] = "Johnson";

    //Fill A2:B6 with an array of values (First and Last Names).
    oSheet.get_Range("A2", "B6").Value2 = saNames;

    //Fill C2:C6 with a relative formula (=A2 & " " & B2).
    oRng = oSheet.get_Range("C2", "C6");
    oRng.Formula = "=A2 & \" \" & B2";

    //Fill D2:D6 with a formula(=RAND()*100000) and apply format.
    oRng = oSheet.get_Range("D2", "D6");
    oRng.Formula = "=RAND()*100000";
    oRng.NumberFormat = "$0.00";

    //AutoFit columns A:D.
    oRng = oSheet.get_Range("A1", "D1");
    oRng.EntireColumn.AutoFit();

    oXL.Visible = false;
    oXL.UserControl = false;
    oWB.SaveAs("c:\\test\\test505.xls", Microsoft.Office.Interop.Excel.XlFileFormat.xlWorkbookDefault, Type.Missing, Type.Missing,
        false, false, Microsoft.Office.Interop.Excel.XlSaveAsAccessMode.xlNoChange,
        Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing);

    oWB.Close();
    oXL.Quit();

    //...

您可以使用ClosedXML来实现这一点。
将表存储在DataTable中，然后可以通过以下简单代码段将表导出到Excel：

XLWorkbook workbook = new XLWorkbook();
DataTable table = GetYourTable();
workbook.Worksheets.Add(table );

您可以阅读ClosedXML的文档来了解更多信息。希望这对您有所帮助！

希望这里正是我们要找的。

private void button2_Click(object sender, RoutedEventArgs e)
{
    UpdateExcel("Sheet3", 4, 7, "Namachi@gmail");
}

private void UpdateExcel(string sheetName, int row, int col, string data)
{
    Microsoft.Office.Interop.Excel.Application oXL = null;
    Microsoft.Office.Interop.Excel._Workbook oWB = null;
    Microsoft.Office.Interop.Excel._Worksheet oSheet = null;

    try
    {
        oXL = new Microsoft.Office.Interop.Excel.Application();
        oWB = oXL.Workbooks.Open("d:\\MyExcel.xlsx");
        oSheet = String.IsNullOrEmpty(sheetName) ? (Microsoft.Office.Interop.Excel._Worksheet)oWB.ActiveSheet : (Microsoft.Office.Interop.Excel._Worksheet)oWB.Worksheets[sheetName];

        oSheet.Cells[row, col] = data;

        oWB.Save();

        MessageBox.Show("Done!");
    }
    catch (Exception ex)
    {
        MessageBox.Show(ex.ToString());
    }
    finally
    {
        if (oWB != null)
        oWB.Close();
    }
}

使用Microsoft.Jet.OLEDB.4.0和OleDb可以写入excel文件而不打开它。使用OleDb，它的行为就像使用sql写入表一样。
下面是我用来创建和写入一个新excel文件的代码，不需要额外的引用

var connectionString = @"Provider=Microsoft.Jet.OLEDB.4.0;Data Source=C:\SomePath\ExcelWorkBook.xls;Extended Properties=Excel 8.0";
using (var excelConnection = new OleDbConnection(connectionString))
{
    // The excel file does not need to exist, opening the connection will create the
    // excel file for you
    if (excelConnection.State != ConnectionState.Open) { excelConnection.Open(); }

    // data is an object so it works with DBNull.Value
    object propertyOneValue = "cool!";
    object propertyTwoValue = "testing";

    var sqlText = "CREATE TABLE YourTableNameHere ([PropertyOne] VARCHAR(100), [PropertyTwo] INT)";

    // Executing this command will create the worksheet inside of the workbook
    // the table name will be the new worksheet name
    using (var command = new OleDbCommand(sqlText, excelConnection)) { command.ExecuteNonQuery(); }

    // Add (insert) data to the worksheet
    var commandText = $"Insert Into YourTableNameHere ([PropertyOne], [PropertyTwo]) Values (@PropertyOne, @PropertyTwo)";

    using (var command = new OleDbCommand(commandText, excelConnection))
    {
        // We need to allow for nulls just like we would with
        // sql, if your data is null a DBNull.Value should be used
        // instead of null 
        command.Parameters.AddWithValue("@PropertyOne", propertyOneValue ?? DBNull.Value);
        command.Parameters.AddWithValue("@PropertyTwo", propertyTwoValue ?? DBNull.Value);

        command.ExecuteNonQuery();
    }
}

最近，我试用了npoi，它非常简单。
按照要求，让我们编写将数据输出到work1_4.13.14.xlsx文件的代码，如下所示：

Name   Age  City
Ben    20   xyz
Jack   25   xyz
Mike   45   zyx

下面是代码

using NPOI.SS.UserModel;
using NPOI.XSSF.UserModel;
using System.IO;

namespace ExcelWriter
{
    class Program
    {
        static void Main(string[] args)
        {
            IWorkbook workbook = new XSSFWorkbook();
            ISheet sheet1 = workbook.CreateSheet("Sheet1");

            IRow row1 = sheet1.CreateRow(0);
            row1.CreateCell(0).SetCellValue("Name");
            row1.CreateCell(1).SetCellValue("Age");
            row1.CreateCell(2).SetCellValue("City");

            IRow row2 = sheet1.CreateRow(1);
            row2.CreateCell(0).SetCellValue("Ben");
            row2.CreateCell(1).SetCellValue("20");
            row2.CreateCell(2).SetCellValue("xyz");

            IRow row3 = sheet1.CreateRow(2);
            row3.CreateCell(0).SetCellValue("Jack");
            row3.CreateCell(1).SetCellValue("25");
            row3.CreateCell(2).SetCellValue("xyz");

            IRow row4 = sheet1.CreateRow(3);
            row4.CreateCell(0).SetCellValue("Mike");
            row4.CreateCell(1).SetCellValue("45");
            row4.CreateCell(2).SetCellValue("zyx");

            FileStream sw = File.Create("work1_4.13.14.xlsx");
            workbook.Write(sw);
            sw.Close();
        }
    }
}

我使用循环不仅仅是为了让初学者容易理解。
.CreateRow(int index)在指定索引处创建新行。
row.CreateCell(int index)在行的指定索引处创建新单元格。
cell.SetCellValue(string value)在行索引处设置值。

了解更多信息：

块体：https://www.nuget.org/packages/NPOI
代码：https://github.com/nissl-lab/npoi
示例：https://github.com/nissl-lab/npoi-examples

只需按照以下步骤操作：
//启动Excel并获取Application对象。

oXL = new Microsoft.Office.Interop.Excel.Application();

oXL.Visible = false;