你应该发射

proj.Configuration = polyspace.ModelLinkOptions(ModelName);

紧接着

proj=polyspace.Project;

而不是在所有命令的末尾，因为polyspace.ModelLinkOptions将再次加载项目，然后重置先前设置的选项。尝试如下操作：

ModelName = 'MyModel';
open_system(ModelName);
proj=polyspace.Project;
proj.Configuration = polyspace.ModelLinkOptions(ModelName);
proj.Configuration=polyspace.Options('C');
proj.Configuration.TargetCompiler.Compiler = 'generic';
proj.Configuration.CodingRulesCodeMetrics.EnableMisraC3 = true;
proj.Configuration.CodingRulesCodeMetrics.MisraC3Subset = 'mandatory-required';

proj.Configuration.ResultsDir = fullfile(pwd,'results');
run(proj, 'bugFinder');