你首先得到React对象，然后你删除它。文档
验证码：

@bot.slash_command(name='removereaction', description="I'm helping someone with their Stack post")
async def removereaction(ctx, message: discord.Option(discord.Message)):
    print(message)
    for i in message.reactions:
        async for user in i.users():
            await i.remove(user)
    await ctx.respond(message.reactions)

它的工作原理是从discord.Option类型的参数message中获取消息。设置discord.Option，以便您可以使用来自链接或ID的消息。然后，它使用此参数循环所有消息的React。然后它循环每个与该ReactReactReact的用户。它必须是异步的，因为i.users（）是异步的（参见here）。
完整的代码可以帮助你：

import discord
from discord.ext import commands

intents = discord.Intents().all()

bot = commands.Bot(intents=intents)

@bot.event

async def on_message(message):
    if message.author == bot.user:
        return
    if message.content == 'test':
        me = await message.reply('Is this cool?')
        await me.add_reaction("👎")
        await me.add_reaction("👍")
        try:
            reaction, user = await bot.wait_for("reaction_add", check=lambda reaction, user: 
user == message.author and reaction.emoji in ["👎", "👍"], timeout=30.0)

        except asyncio.TimeoutError:
            await message.reply("Tmieout bro")
        else:
            if reaction.emoji == "👍":
                await message.reply('Like it.')
                async for user in reaction.users():
                    await reaction.remove(user)

            else:
                await message.reply("NO like")
                async for user in reaction.users():
                    await reaction.remove(user)

如果你想删除JUST机器人的React，请更改以下行：

async for user in reaction.users():
                        await reaction.remove(user)

收件人：

await reaction.remove(bot.user)