使用ColWidths属性，如下所示：

with StringGrid1 do
  ColWidths[1] := ClientWidth - ColWidths[0] - 2 * GridLineWidth;

为了获得更健壮和灵活的解决方案，考虑所有固定列并参数化列索引：

procedure SetColumnFullWidth(Grid: TStringGrid; ACol: Integer);
var
  I: Integer;
  FixedWidth: Integer;
begin
  with Grid do
    if ACol >= FixedCols then
    begin
      FixedWidth := 0;
      for I := 0 to FixedCols - 1 do
        Inc(FixedWidth, ColWidths[I] + GridLineWidth);
      ColWidths[ACol] := ClientWidth - FixedWidth - GridLineWidth;
    end;
end;

procedure TForm1.Button1Click(Sender: TObject);
begin
  SetColumnFullWidth(StringGrid1, 4);
end;

下面的代码使用FixedCols = 0（以适应其他值，例如：FixedCols = 1 ==> for Col := 1 to ...）

procedure AutoSizeGridColumns(Grid: TStringGrid);
const
  MIN_COL_WIDTH = 15;
var
  Col : Integer;
  ColWidth, CellWidth: Integer;
  Row: Integer;
begin
  Grid.Canvas.Font.Assign(Grid.Font);
  for Col := 0 to Grid.ColCount -1 do
  begin
    ColWidth := Grid.Canvas.TextWidth(Grid.Cells[Col, 0]);
    for Row := 0 to Grid.RowCount - 1 do 
    begin
      CellWidth := Grid.Canvas.TextWidth(Grid.Cells[Col, Row]);
      if CellWidth > ColWidth then
        Grid.ColWidths[Col] := CellWidth + MIN_COL_WIDTH
      else
        Grid.ColWidths[Col] := ColWidth + MIN_COL_WIDTH;
    end;
  end;
end;

这样更好：

procedure AutoSizeGridColumns(Grid: TStringGrid);
const
  MIN_COL_WIDTH = 15;
var
  Col : Integer;
  ColWidth, CellWidth: Integer;
  Row: Integer;
begin
  Grid.Canvas.Font.Assign(Grid.Font);
  for Col := 0 to Grid.ColCount -1 do
  begin
    ColWidth := Grid.Canvas.TextWidth(Grid.Cells[Col, 0]);
    for Row := 0 to Grid.RowCount - 1 do 
    begin
      CellWidth := Grid.Canvas.TextWidth(Grid.Cells[Col, Row]);
      if CellWidth > ColWidth then
        ColWidth := CellWidth
    end;
    Grid.ColWidths[Col] := ColWidth + MIN_COL_WIDTH;
  end;
end;

解决方案如果有更多疑问命令“grid.AutoFitColumns（）”其中grid是一个“TAdvStringGrid”;
;）

签收
允许您根据容器的大小（给定内容的维度）动态调整列的大小
你可以直接粘贴，它将工作的权利开箱即用。我不解释了，我没时间。谁愿意或者谁真的需要找时间来理解这段代码，尤其是因为它非常简单

procedure AutoSizeGridColumns(Grid: TStringGrid);
    var
      ACol, ARow: Integer;
      GridWidth, ColWidth, ColsCount: Integer;
      ColWidthDifferenceWidth, ColMinWidth, ColsSumWidth: Integer;
    begin
      GridWidth := Grid.Width;
      ColsCount := Grid.ColCount;      
      ColWidth := 0;
      ColsSumWidth := 0;
      ColWidthDifferenceWidth := 0;
    
      Grid.Canvas.Font.Assign(Grid.Font);
      for ACol := 0 to ColsCount - 1 do
      begin
    
        for ARow := 0 to Grid.RowCount - 1 do
        begin
          ColMinWidth := Grid.Canvas.TextWidth(Grid.Cells[ACol, ARow]);
        end;
    
        ColsSumWidth := ColsSumWidth + ColMinWidth;
        Grid.ColWidths[ACol] := ColMinWidth;
      end;
           
      if ColsSumWidth < GridWidth then
        begin
          ColWidthDifferenceWidth := (GridWidth - ColsSumWidth) div ColsCount - 1;
    
          for ACol := 0 to ColsCount - 1 do
          begin
            Grid.ColWidths[ACol] := Grid.ColWidths[ACol] + ColWidthDifferenceWidth;
          end;
        end
      else
        begin
          ColWidthDifferenceWidth := (ColsSumWidth - GridWidth) div ColsCount;
    
          for ACol := 0 to ColsCount - 1 do
          begin
            Grid.ColWidths[ACol] := Grid.ColWidths[ACol] - ColWidthDifferenceWidth;
          end;
        end;
    end;