这是不可能做到这一点与时间线，时间线只是循环时，你传递loop: true的创建。从源代码看，添加的对象中的loop属性似乎被忽略了。
但是，您可以在anime示例上使用promise .finished：

anime({/*first animation*/}).finished.then(()=>
anime({/*next animation*/}))

并模仿继承属性：

let base = {
  easing: 'easeOutExpo',
  targets: '.fles',
}

anime(Object.assign({}, base, {
  rotate: 20,
  duration: 750,
  loop: false,
}))
.finished.then(()=>
  anime(Object.assign({}, base, {
    duration: 6000,
    loop: true,
    easing: 'easeInOutQuad',
    keyframes: [
      {rotate: '+=1'},
      {rotate: '-=1'},
      {rotate: '+=1.5'},
      {rotate: '-=2'},
      {rotate: '+=1.5'},
    ],
  })));

这可以通过使用内部和外部<div>来解决。在其中一个上放置循环动画，在另一个上放置打开动画。

<div id="outer">
  <div id="inner">
    Foo
  </div>
</div>

// opening animation
anime({
  targets: '#outer',
  scale: [0, 1],
  loop: false
});

// looping animation
anime({
  targets: '#inner',
  rotate: [-5, 5],
  loop: true,
  direction: 'alternate'
});

只是想跟进@WerWet的答案，你也可以用时间表来做这件事。在我的例子中，我对SVG应用了一系列效果，并在页面加载时对文本进行动画处理，但希望文本在完成加载动画后无限期地出现故障。我是这么做的...
（我使用react，因此在useEffect钩子中调用了animation()）

const animation = () => {
  const timeline = anime.timeline()
    timeline.add({
    targets: ".path",
    strokeDashoffset: [anime.setDashoffset, 0],
    easing: "easeInOutSine",
    duration: 1500,
    delay: function (el, i) {
      return i * 250
    },
  })
  timeline.add({
    targets: ".logo-main",
    duration: 20,
    skewX: 40,
    easing: "easeInOutQuad",
  })
  timeline.add({
    targets: ".logo-main",
    duration: 20,
    skewY: 40,
    easing: "easeInOutQuad",
  })
  timeline.add({
    targets: ".logo-main",
    duration: 20,
    skewX: -40,
    easing: "easeInOutQuad",
  })
  timeline.add({
    targets: ".logo-main",
    duration: 70,
    skewX: 0,
    skewY: 0,
    easing: "easeInOutQuad",
  })
  timeline.add({
    targets: ".logo-main",
    duration: 70,
    opacity: 0,
    easing: "easeInOutQuad",
  })
  timeline.add({
    targets: ".logo-main",
    filter: "drop-shadow(0px 0px 20px rgba(43, 251, 251, 1))",
    opacity: 1,
    easing: "easeInOutSine",
    duration: 1000,
    direction: "alternate",
  })
  timeline.add({
    targets: ".letter",
    opacity: [0, 0.75],
    translateY: [-600, 0],
    easing: "easeOutExpo",
    duration: 1400,
    delay: (el, i) => 50 * (i + 1),
    endDelay: 500,
  })

  timeline.play()
  timeline.finished.then(() => {
    const timelineText = anime.timeline({ loop: true })
    timelineText.add({
      targets: ".letter",
      duration: 70,
      skewX: 70,
      easing: "easeInOutQuad",
    })
    timelineText.add({
      targets: ".letter",
      duration: 70,
      skewX: 0,
      easing: "easeInOutQuad",
    })
    timelineText.add({
      targets: ".letter",
      duration: 7000,
    })
  })
}

希望这有帮助！