您必须在 Package 器类中实现INotifyPropertyChanged，才能使任何双向绑定工作。参见example on MSDN
此外，不确定绑定到DataGridRow的IsSelected属性是否是正确的方法，而是尝试在ViewModel（托管ListOfElementParameterWrappers的类）中创建一个SelectedItem属性，并将其绑定到xaml中DataGrid的SelectedItem属性。ListOfElementParameterWrappers的类型应该是ObservableCollection<ElementParameterWrapper>，而不是一般列表（see this article）。
生成的代码可能如下所示：

wrapper类：

public class ElementParameterWrapper:INotifyPropertyChanged
{
    public ElementParameterWrapper(Parameter parameter)
    {
        Name = parameter.Definition.Name;
        Id = parameter.Id;
        if (parameter.IsShared)
        {
            GUID = parameter.GUID;
        }
    }

    public event PropertyChangedEventHandler PropertyChanged;

    public string Name { get; set; }
    public ElementId Id { get; set; }
    public Guid GUID { get; set; }
    private bool isObjectSelected;
    public bool IsObjectSelected
    {
        get { return isObjectSelected; }
        set { 
            isObjectSelected = value;
            OnPropertyChanged();
        }
    }
    
    protected void OnPropertyChanged([CallerMemberName] string name = null)
    {
        PropertyChanged?.Invoke(this, new PropertyChangedEventArgs(name));
    }
}

ViewModel类：

public class MyViewModel : INotifyPropertyChanged
{
    public MyViewModel (ICollection wrapperCollection){
        ListOfElementParameterWrappers = new ObservableCollection<ElementParameterWrapper>(wrapperCollection);
        SelectedItem = ListOfElementParameterWrappers.FirstOrDefault();
    }
      
    public ObservableCollection<ElementParameterWrapper> ListOfElementParameterWrappers {get; set;}
      
    private ElementParameterWrapper _selecteItem;
    //this property keeps track of the currently selected item in the DataGrid
    public ElementParameterWrapper SelectedItem {
        get {return _selectedItem;}
        set {
            _selectedItem = value;
            //If you need to also change the value of the IsSelected
            //property of the selected item you can do something like this
            foreach (var item in ListOfElementParameterWrappers){
                item.IsObjectSelected= false;
            }
            _selectedItem.IsObjectSelected= true;
            //finally fire the PropertyChanged event
            OnPrepertyChanged();
        }
    }

    public event PropertyChangedEventHandler PropertyChanged;
    protected void OnPropertyChanged([CallerMemberName] string name = null)
    {
        PropertyChanged?.Invoke(this, new PropertyChangedEventArgs(name));
    }
}

xaml：

<DataGrid Grid.Row="1"
          Grid.Column="0"
          HorizontalAlignment="Left"
          Margin="10,0,10,10"
          ItemsSource="{Binding ListOfElementParameterWrappers, Mode=TwoWay, UpdateSourceTrigger=PropertyChanged}"
 
          SelecteItem="{Binding SelectedItem, Mode=TwoWay, UpdateSourceTrigger=PropertyChanged}"

          RowStyle="{StaticResource RowToBeSelectedStyle}"
          AutoGenerateColumns="False"
          VerticalScrollBarVisibility="Auto"
          HorizontalScrollBarVisibility="Hidden"
          CanUserAddRows="False"
          CanUserResizeColumns="False"
          CanUserSortColumns="False"
          IsReadOnly="False"
          SelectionMode="Single"
          SelectionUnit="FullRow">
</DataGrid>