我正在尝试让Circos安装在我的Mac上（OS Catalina 版本10. 15. 7），我在Perl中工作时遇到了臭名昭著的GD的问题。我已经在网上尝试了几种解决方案，并删除了一切从头开始，但仍然不能让这个dang库工作。最近，我尝试了安装circos的方法，然后安装所有其他依赖项，并以安装GD结束，但这并不奏效。
当我运行“circos”命令时，我得到这样的输出（1）：所有其他必要的模块都安装好了，如“circos -modules”所示（2）
我已经尝试使用CPAN安装GD，它也错误的给出下面的错误开始在“结果：失败”。（3）
奇怪的是，我的电脑识别出我安装了GD，因为当我调用gdlib-config --all时，它会给我GD库的输出（4）。看起来GD可能在那里，但不知何故没有链接到Perl？我错过了一些超级简单的东西吗？任何帮助都将不胜感激。我为任何无知道歉，我仍然是一个使用终端的业余爱好者。
我也试过perlbrew，得到了同样的点和同样的错误。
Circos和Perl都在我的路径中（如下所示）。
（一）

Mon Jun 14 ashleyschumann ~circos

*** REQUIRED MODULE(S) MISSING OR OUT-OF-DATE ***

You are missing one or more Perl modules, require newer versions, or some modules failed to load. Use CPAN to install it as described in this tutorial

http://www.circos.ca/documentation/tutorials/configuration/perl_and_modules

missing GD::Polyline
  error Attempt to reload GD.pm aborted.Compilation failed in require at /Users/ashleyschumann/perl5/lib/perl5/darwin-2level/GD/Polyline.pm line 45.
missing GD
  error Can't load '/Users/ashleyschumann/perl5/lib/perl5/darwin-2level/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/perl5/lib/perl5/darwin-2level/auto/GD/GD.bundle, 1): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib  Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib  Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197. at (eval 42) line 1.Compilation failed in require at (eval 42) line 1.

（二）

Mon Jun 14 ashleyschumann ~circos -modules
ok       1.52 Carp
ok       0.45 Clone
ok       2.63 Config::General
ok       3.80 Cwd
ok      2.179 Data::Dumper
ok       2.58 Digest::MD5
ok       2.85 File::Basename
ok       3.80 File::Spec::Functions
ok     0.2311 File::Temp
ok       1.52 FindBin
ok       0.39 Font::TTF::Font
missing            GD
missing            GD::Polyline
ok       2.52 Getopt::Long
ok       1.46 IO::File
ok      0.430 List::MoreUtils
ok       1.55 List::Util
ok       0.01 Math::Bezier
ok   1.999818 Math::BigFloat
ok       0.07 Math::Round
ok       0.08 Math::VecStat
ok    1.03_01 Memoize
ok       1.97 POSIX
ok       1.30 Params::Validate
ok       2.01 Pod::Usage
ok       2.05 Readonly
ok 2017060201 Regexp::Common
ok       2.86 SVG
ok       1.19 Set::IntSpan
ok     1.6611 Statistics::Basic
ok       3.23 Storable
ok       1.23 Sys::Hostname
ok       2.04 Text::Balanced
ok       0.62 Text::Format
ok     1.9767 Time::HiRes

（三）

Test Summary Report
-------------------
t/fork.t                (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: No plan found in TAP output
t/GD.t                  (Wstat: 9 Tests: 2 Failed: 2)
  Failed tests:  1-2
  Non-zero wait status: 9
  Parse errors: Bad plan.  You planned 14 tests but ran 2.
t/HSV.t                 (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: Bad plan.  You planned 1 tests but ran 0.
t/Polyline.t            (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: Bad plan.  You planned 1 tests but ran 0.
t/transp.t              (Wstat: 6400 Tests: 1 Failed: 1)
  Failed test:  1
  Non-zero exit status: 25
  Parse errors: Bad plan.  You planned 12 tests but ran 1.
Files=9, Tests=3, 152 wallclock secs ( 0.05 usr  0.03 sys + 106.75 cusr 19.56 csys = 126.39 CPU)
Result: FAIL
Failed 5/9 test programs. 3/3 subtests failed.
make: *** [Makefile:1157: test_dynamic] Error 255
  RURBAN/GD-2.73.tar.gz
  /Users/ashleyschumann/opt/anaconda3/bin/make test -- NOT OK
//hint// to see the cpan-testers results for installing this module, try:
  reports RURBAN/GD-2.73.tar.gz
Failed during this command:
 RURBAN/GD-2.73.tar.gz                        : make_test NO

(4)
Mon Jun 14 ashleyschumann ~/circos-0.69-9/GD-2.51gdlib-config --all
GD library  2.1.0
includedir: /usr/local/include
cflags:     -I/usr/local/include
ldflags:    -Wl,-pie -Wl,-headerpad_max_install_names -Wl,-dead_strip_dylibs -Wl,-rpath,/Users/ashleyschumann/opt/anaconda3/lib -L/Users/ashleyschumann/opt/anaconda3/lib -L/usr/X11/lib -L/usr/local/lib
libs:       -ljpeg -lz  -L/usr/local/lib -lpng16 -L/usr/local/opt/freetype/lib -lfreetype -L/usr/local/Cellar/fontconfig/2.13.1/lib -L/usr/local/opt/freetype/lib -lfontconfig -lfreetype -lfontconfig -L/usr/local/Cellar/libtiff/4.2.0/lib -ltiff -liconv
libdir:     /usr/local/lib
features:   GD_TIFF GD_JPEG GD_FONTCONFIG GD_FREETYPE GD_PNG GD_GIF GD_GIFANIM GD_OPENPOLYGON

路径

/Users/ashleyschumann/Applications/BLAST/ncbi-blast-2.11.0+:/Users/ashleyschumann/perl5/perlbrew/bin:/Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/bin:/Users/ashleyschumann/ashleyschumann/Applications/Circos/bin:/Library/Frameworks/Python.framework/Versions/3.8/bin:/Library/Frameworks/Python.framework/Versions/3.7/bin:/anaconda3/bin:/Users/ashleyschumann/perl5/bin:/ashleyschumann/Applications/Circos/bin/libgd/libgd-2.2.3/config:/Users/ashleyschumann/current/bin:/usr/bin/perl:/Users/ashleyschumann/opt/anaconda3/bin:/Users/ashleyschumann/opt/anaconda3/condabin:/usr/local/bin:/usr/bin:/bin:/usr/sbin:/sbin:/opt/X11/bin:/Users/ashleyschumann/bin:/Users/ashleyschumann/Applications/circos/current/bin/circos:/Users/ashleyschumann/Applications/circos/bin:/dropbox/RAW_DATA

Upon running Håkon's suggestion, I got this error following the use of "make test

Tue Jun 15 ashleyschumann ~/GD-2.73make test
"/Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/bin/perl" -MExtUtils::Command::MM -e 'cp_nonempty' -- GD.bs blib/arch/auto/GD/GD.bs 644
PERL_DL_NONLAZY=1 "/Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/bin/perl" "-MExtUtils::Command::MM" "-MTest::Harness" "-e" "undef *Test::Harness::Switches; test_harness(0, 'blib/lib', 'blib/arch')" t/*.t
t/fork.t .................. Can't load '/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle, 2): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib
  Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib
  Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197.
 at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
Compilation failed in require at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
BEGIN failed--compilation aborted at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
Compilation failed in require at t/fork.t line 3.
BEGIN failed--compilation aborted at t/fork.t line 3.
t/fork.t .................. Dubious, test returned 2 (wstat 512, 0x200)
No subtests run
t/GD.t .................... 1/14
#   Failed test 'use GD;'
#   at t/GD.t line 14.
#     Tried to use 'GD'.
#     Error:  Can't load '/Users/ashleyschumann/GD-2.73/t/../blib/arch/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/GD-2.73/t/../blib/arch/auto/GD/GD.bundle, 2): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib
#   Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib
#   Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197.
#  at t/GD.t line 14.
# Compilation failed in require at t/GD.t line 14.
# BEGIN failed--compilation aborted at t/GD.t line 14.

#   Failed test 'use GD::Simple;'
#   at t/GD.t line 15.
#     Tried to use 'GD::Simple'.
#     Error:  Attempt to reload GD.pm aborted.
# Compilation failed in require at /Users/ashleyschumann/GD-2.73/t/../blib/lib/GD/Simple.pm line 160.
# BEGIN failed--compilation aborted at /Users/ashleyschumann/GD-2.73/t/../blib/lib/GD/Simple.pm line 160.
# Compilation failed in require at t/GD.t line 15.
# BEGIN failed--compilation aborted at t/GD.t line 15.
t/GD.t .................... Failed 14/14 subtests
t/HSV.t ................... Can't load '/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle, 2): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib
  Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib
  Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197.
 at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
Compilation failed in require at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
BEGIN failed--compilation aborted at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Simple.pm line 160.
Compilation failed in require at t/HSV.t line 14.
BEGIN failed--compilation aborted at t/HSV.t line 14.
# Looks like your test exited with 2 before it could output anything.
t/HSV.t ................... Dubious, test returned 2 (wstat 512, 0x200)
Failed 1/1 subtests
t/Polyline.t .............. Can't load '/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle, 2): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib
  Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib
  Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197.
 at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Polyline.pm line 45.
Compilation failed in require at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Polyline.pm line 45.
BEGIN failed--compilation aborted at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Polyline.pm line 45.
Compilation failed in require at t/Polyline.t line 10.
BEGIN failed--compilation aborted at t/Polyline.t line 10.
t/Polyline.t .............. Dubious, test returned 2 (wstat 512, 0x200)
Failed 1/1 subtests
t/transp.t ................ 1/12
#   Failed test 'use GD;'
#   at t/transp.t line 8.
#     Tried to use 'GD'.
#     Error:  Can't load '/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle' for module GD: dlopen(/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle, 2): Library not loaded: /usr/local/opt/libpng/lib/libpng16.16.dylib
#   Referenced from: /usr/local/opt/freetype/lib/libfreetype.6.dylib
#   Reason: Incompatible library version: libfreetype.6.dylib requires version 54.0.0 or later, but libpng16.16.dylib provides version 31.0.0 at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/darwin-2level/DynaLoader.pm line 197.
#  at t/transp.t line 8.
# Compilation failed in require at t/transp.t line 8.
# BEGIN failed--compilation aborted at t/transp.t line 8.
Use of uninitialized value $pkg in concatenation (.) or string at /Users/ashleyschumann/perl5/perlbrew/perls/perl-5.34.0/lib/5.34.0/Symbol.pm line 131.
Can't locate object method "_newFromGif" via package "GD::Image" at /Users/ashleyschumann/GD-2.73/blib/lib/GD/Image.pm line 196.
# Looks like your test exited with 25 just after 1.
t/transp.t ................ Dubious, test returned 25 (wstat 6400, 0x1900)
Failed 12/12 subtests
t/z_kwalitee.t ............ skipped: No RELEASE_TESTING
t/z_manifest.t ............ skipped: requires a git checkout and a unix for git and diff
t/z_pod-spell-mistakes.t .. skipped: No RELEASE_TESTING
t/z_pod.t ................. skipped: No RELEASE_TESTING

Test Summary Report
-------------------
t/fork.t                (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: No plan found in TAP output
t/GD.t                  (Wstat: 9 Tests: 2 Failed: 2)
  Failed tests:  1-2
  Non-zero wait status: 9
  Parse errors: Bad plan.  You planned 14 tests but ran 2.
t/HSV.t                 (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: Bad plan.  You planned 1 tests but ran 0.
t/Polyline.t            (Wstat: 512 Tests: 0 Failed: 0)
  Non-zero exit status: 2
  Parse errors: Bad plan.  You planned 1 tests but ran 0.
t/transp.t              (Wstat: 6400 Tests: 1 Failed: 1)
  Failed test:  1
  Non-zero exit status: 25
  Parse errors: Bad plan.  You planned 12 tests but ran 1.
Files=9, Tests=3, 163 wallclock secs ( 0.04 usr  0.03 sys + 106.76 cusr 20.47 csys = 127.30 CPU)
Result: FAIL
Failed 5/9 test programs. 3/3 subtests failed.
make: *** [Makefile:1157: test_dynamic] Error 255

(base) Tue Jun 15 ashleyschumann ~pkg-config --debug libpng
no output option set, defaulting to --exists
Error printing disabled by default due to use of output options --exists, --atleast/exact/max-version, --list-all or no output option at all. Value of --print-errors: 0
Error printing disabled
Adding virtual 'pkg-config' package to list of known packages
Looking for package 'libpng'
Looking for package 'libpng-uninstalled'
Reading 'libpng' from file '/usr/local/lib/pkgconfig/libpng.pc'
Parsing package file '/usr/local/lib/pkgconfig/libpng.pc'
  line>prefix=/usr/local/Cellar/libpng/1.6.37
 Variable declaration, 'prefix' has value '/usr/local/Cellar/libpng/1.6.37'
  line>exec_prefix=${prefix}
 Variable declaration, 'exec_prefix' has value '/usr/local/Cellar/libpng/1.6.37'
  line>libdir=${exec_prefix}/lib
 Variable declaration, 'libdir' has value '/usr/local/Cellar/libpng/1.6.37/lib'
  line>includedir=${prefix}/include/libpng16
 Variable declaration, 'includedir' has value '/usr/local/Cellar/libpng/1.6.37/include/libpng16'
  line>
  line>Name: libpng
  line>Description: Loads and saves PNG files
  line>Version: 1.6.37
  line>Requires: zlib
  line>Libs: -L${libdir} -lpng16
  line>Libs.private: -lz
Unknown keyword 'Libs.private' in '/usr/local/lib/pkgconfig/libpng.pc'
  line>Cflags: -I${includedir}
Path position of 'libpng' is 1
Adding 'libpng' to list of known packages
Searching for 'libpng' requirement 'zlib'
Looking for package 'zlib'
Looking for package 'zlib-uninstalled'
Reading 'zlib' from file '/usr/local/Homebrew/Library/Homebrew/os/mac/pkgconfig/10.15/zlib.pc'
Parsing package file '/usr/local/Homebrew/Library/Homebrew/os/mac/pkgconfig/10.15/zlib.pc'
  line>homebrew_sdkroot=/Library/Developer/CommandLineTools/SDKs/MacOSX10.15.sdk
 Variable declaration, 'homebrew_sdkroot' has value '/Library/Developer/CommandLineTools/SDKs/MacOSX10.15.sdk'
  line>prefix=${homebrew_sdkroot}/usr
 Variable declaration, 'prefix' has value '/Library/Developer/CommandLineTools/SDKs/MacOSX10.15.sdk/usr'
  line>exec_prefix=/usr
 Variable declaration, 'exec_prefix' has value '/usr'
  line>libdir=${exec_prefix}/lib
 Variable declaration, 'libdir' has value '/usr/lib'
  line>sharedlibdir=${libdir}
 Variable declaration, 'sharedlibdir' has value '/usr/lib'
  line>includedir=${prefix}/include
 Variable declaration, 'includedir' has value '/Library/Developer/CommandLineTools/SDKs/MacOSX10.15.sdk/usr/include'
  line>
  line>Name: zlib
  line>Description: zlib compression library
  line>Version: 1.2.11
  line>
  line>Requires:
  line>Libs: -L${libdir} -L${sharedlibdir} -lz
  line>Cflags:
Path position of 'zlib' is 4
Adding 'zlib' to list of known packages
Package zlib has -L /usr/lib in Libs
Removing -L /usr/lib from libs for zlib
Package zlib has -L /usr/lib in Libs
Removing -L /usr/lib from libs for zlib

~ ~ ~

/Users/ashleyschumann/GD-2.73/blib/arch/auto/GD/GD.bundle:
    /usr/local/lib/libjpeg.9.dylib (compatibility version 10.0.0, current version 10.0.0)
    @rpath/libz.1.dylib (compatibility version 1.0.0, current version 1.2.11)
    /usr/local/lib/libpng16.16.dylib (compatibility version 31.0.0, current version 31.0.0)
    /usr/local/opt/freetype/lib/libfreetype.6.dylib (compatibility version 24.0.0, current version 24.4.0)
    /usr/local/opt/fontconfig/lib/libfontconfig.1.dylib (compatibility version 14.0.0, current version 14.0.0)
    /usr/local/opt/libtiff/lib/libtiff.5.dylib (compatibility version 12.0.0, current version 12.0.0)
    @rpath/libiconv.2.dylib (compatibility version 9.0.0, current version 9.1.0)
    /usr/local/lib/libgd.3.dylib (compatibility version 4.0.0, current version 4.0.0)
    /usr/lib/libSystem.B.dylib (compatibility version 1.0.0, current version 1281.100.1)