springboot项目，运行环境Linux，
mysql:5.6.46
druid-spring-boot-starter:1.1.21
mysql-connector-java:5.1.46
配置
url: jdbc:mysql://xxxx（脱敏处理）:3306/xxxxx（脱敏处理）?useUnicode=true&characterEncoding=UTF-8&serverTimezone=UTC&allowPublicKeyRetrieval=true&verifyServerCertificate=false&useSSL=false&autoReconnect=true&failOverReadOnly=false
driver-class-name: com.mysql.jdbc.Driver
username: xxxxxx（脱敏处理）
password: xxxxxx（脱敏处理）
initial-size: 10
max-active: 50
min-idle: 10
max-wait: 60000
pool-prepared-statements: true
max-pool-prepared-statement-per-connection-size: 20
validation-query: SELECT 1 FROM DUAL
test-on-borrow: true
test-on-return: false
test-while-idle: true
time-between-eviction-runs-millis: 60000
filters: stat,wall

以下报错信息大概在10分钟出现一次。尝试很多办法都为解决。请问druid是否有关解决方案？
2020-08-22 02:10:06,338 ERROR [Druid-ConnectionPool-Create-534666530] c.alibaba.druid.pool.DruidDataSource [DruidDataSource.java : 2755] create connection SQLException, url: jdbc:mysql://xxxxx（脱敏处理）:3306/xxxx（脱敏处理）?useUnicode=true&characterEncoding=UTF-8&serverTimezone=UTC&allowPublicKeyRetrieval=true&verifyServerCertificate=false&useSSL=false&autoReconnect=true&failOverReadOnly=false, errorCode 0, state 08001
com.mysql.jdbc.exceptions.jdbc4.MySQLNonTransientConnectionException: Could not create connection to database server. Attempted reconnect 3 times. Giving up.
at sun.reflect.NativeConstructorAccessorImpl.newInstance0(Native Method)
at sun.reflect.NativeConstructorAccessorImpl.newInstance(NativeConstructorAccessorImpl.java:62)
at sun.reflect.DelegatingConstructorAccessorImpl.newInstance(DelegatingConstructorAccessorImpl.java:45)
at java.lang.reflect.Constructor.newInstance(Constructor.java:423)
at com.mysql.jdbc.Util.handleNewInstance(Util.java:425)
at com.mysql.jdbc.Util.getInstance(Util.java:408)
at com.mysql.jdbc.SQLError.createSQLException(SQLError.java:919)
at com.mysql.jdbc.SQLError.createSQLException(SQLError.java:898)
at com.mysql.jdbc.SQLError.createSQLException(SQLError.java:887)
at com.mysql.jdbc.SQLError.createSQLException(SQLError.java:861)
at com.mysql.jdbc.ConnectionImpl.connectWithRetries(ConnectionImpl.java:2096)
at com.mysql.jdbc.ConnectionImpl.createNewIO(ConnectionImpl.java:2021)
at com.mysql.jdbc.ConnectionImpl.(ConnectionImpl.java:776)
at com.mysql.jdbc.JDBC4Connection.(JDBC4Connection.java:47)
at sun.reflect.GeneratedConstructorAccessor113.newInstance(Unknown Source)
at sun.reflect.DelegatingConstructorAccessorImpl.newInstance(DelegatingConstructorAccessorImpl.java:45)
at java.lang.reflect.Constructor.newInstance(Constructor.java:423)
at com.mysql.jdbc.Util.handleNewInstance(Util.java:425)
at com.mysql.jdbc.ConnectionImpl.getInstance(ConnectionImpl.java:386)
at com.mysql.jdbc.NonRegisteringDriver.connect(NonRegisteringDriver.java:330)
at com.alibaba.druid.filter.FilterChainImpl.connection_connect(FilterChainImpl.java:156)
at com.alibaba.druid.filter.FilterAdapter.connection_connect(FilterAdapter.java:787)
at com.alibaba.druid.filter.FilterChainImpl.connection_connect(FilterChainImpl.java:150)
at com.alibaba.druid.filter.stat.StatFilter.connection_connect(StatFilter.java:218)
at com.alibaba.druid.filter.FilterChainImpl.connection_connect(FilterChainImpl.java:150)
at com.alibaba.druid.pool.DruidAbstractDataSource.createPhysicalConnection(DruidAbstractDataSource.java:1646)
at com.alibaba.druid.pool.DruidAbstractDataSource.createPhysicalConnection(DruidAbstractDataSource.java:1710)
at com.alibaba.druid.pool.DruidDataSource$CreateConnectionThread.run(DruidDataSource.java:2753)
Caused by: com.mysql.jdbc.exceptions.jdbc4.CommunicationsException: Communications link failure

The last packet sent successfully to the server was 0 milliseconds ago. The driver has not received any packets from the server.
at sun.reflect.GeneratedConstructorAccessor101.newInstance(Unknown Source)
at sun.reflect.DelegatingConstructorAccessorImpl.newInstance(DelegatingConstructorAccessorImpl.java:45)
at java.lang.reflect.Constructor.newInstance(Constructor.java:423)
at com.mysql.jdbc.Util.handleNewInstance(Util.java:425)
at com.mysql.jdbc.SQLError.createCommunicationsException(SQLError.java:990)
at com.mysql.jdbc.MysqlIO.(MysqlIO.java:342)
at com.mysql.jdbc.ConnectionImpl.coreConnect(ConnectionImpl.java:2188)
at com.mysql.jdbc.ConnectionImpl.connectWithRetries(ConnectionImpl.java:2037)
... 17 common frames omitted
Caused by: java.net.ConnectException: Connection refused (Connection refused)
at java.net.PlainSocketImpl.socketConnect(Native Method)
at java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
at java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:206)
at java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:188)
at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
at java.net.Socket.connect(Socket.java:606)
at com.mysql.jdbc.StandardSocketFactory.connect(StandardSocketFactory.java:211)
at com.mysql.jdbc.MysqlIO.(MysqlIO.java:301)
... 19 common frames omitted